Friday, June 6, 2014




For the treatment of following:

1) Seasonal, perennial & vasomotor rhinitis, 2) urticaria, angioneurotic edema, anaphylaxis, 3) pruritus, 4) preanesthetic medication, emesis, motion sickness, 5) miscellaneous including meniere’s
diseases and parkinsonism, 6) cough & cold. Sometimes it may use as a night time sleep aid and for the short-term management of insomnia.

Dosage and Administration

Most allergic conditions are controlled with 25 to 50 mg i.e., (12.5 to 25 ml of syrup) 3 to 4 times a day. Children 6 to 12 years of age : 10 mg i.e.(5 ml of syrup) 3 to 4 times a day.Children 1 to 6 years of age: 5 mg i.e.,

(2.5 ml of syrup) 3 to 4 times a day. In motion sickness: Adults : 25 to 50 mg 3 to 4 times a day. Children (above 9.1 kg): 12.5 to 25 mg 3 to 4 times a day (5mg/ kg/24 hours).

In parkinsonism: Adults: 25 to 50 mg 3 to 4 times a day. Children (above 9.1 kg) : 12.5 to 25 mg 3 to 4 times a day (5mg/ kg/ 24hours).In insomnia: Adults and children over 12 years of old : A dose of 20 to 50 mg is used
as hypnotic in insomnia.

In cough & cold: Adults: 25 mg every 4 hrs. Not to exceed 150 mg in 24 hours. Children (6 to 12 years) : 12.5 mg every 4 hours. Not to exceed 75 mg in 24 hours. Children (2 to 6 years): 6.25 mg every 4 hours.

Contraindication and Precaution

Contraindicated for the premature or newborn infants. Any patients in whom drowsiness is undesirable e.g. drivers, machine operators. Patients with known hypersensitivity to Diphenhydramine or any components of the product. Patients should be cautioned not to operate vehicles or hazardous machinery until their response to the drug has been determined.

Drug Interaction

Antituberculous agent, para-aminosalicylic acid (PAS), alcohol, other CNS depressants (hypnotics, sedatives, tranquilizers, etc), MAO inhibitors.

Side Effect

Side Effects include drowsiness, dizziness, dryness of mouth, blurred vision, nausea and vomiting.

Uses in Pregnancy & Lactation

Should be used in pregnancy only if clearly needed. Use in lactating mother is not recommended.


10 mg/5 ml Syrup


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