Paracetamol

Indication:

Fever, headache, toothache, earache, bodyache, myalgia, dysmenorrhoea, neuralgia and sprains. Pain of colic, back pain, chronic pain of cancer, inflammatory pain, and post-vaccination pain and fever of children. Rheumatism and osteoarthritic pain & stiffness of joints in fingers, hips, knees, wrists, elbows, feet, ankles and top & bottom of the spine.

Dosage & Administration:

 Tablet: Adult 1-2 tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily. Children (6-12 years) 1/2 to 1 tablet 3 to 4 times daily. XR Tablet: 2 tablet every 6 to 8 hourly upto a maximum of 6 tablets daily. Syrup and Suspension: Children Under 3 months: 10 mg/kg body weight (reduce to 5 mg/kg if

jaundiced) 3 to 4 times daily. 3 months to below 1 year : 1/2 to 1 teaspoonful 3 to 4 times daily. 1-5 years: 1-2 teaspoonful 3 to 4 times daily. 6-12 years : 2-4 teaspoonful 3 to 4 times daily. Adults 4-8 teaspoonful 3 to 4 times daily. Paediatric Drop: Children upto 3 months: 0.5 ml (40 mg) 4 to 11 months:

1.0 ml (80 mg). 1 to 2 years: 1.5 ml (120 mg) Dose can be repeated, every 4 hours.

Suppository: Suppository should be administered rectaly. Children 3 months -

1 year : 60-120 mg 4 times daily. Children below 5 years : 125-250 mg, 4 times daily. Children 6-12 years : 250-500 mg, 4 times daily. Adults and children over 12 years : 0.5 - 1 mg, 4 times daily.

Contraindication & Precaution:

 Known sensitivity to paracetamol.

Side Effect:

Side Effects are significantly mild, though haematological reactions

have been reported. Pancreatitis, skin rashes, and other allergic reactions occur

alcoholics or in patients taking other antiepilectic medications.

Precaution:

 Should be given cautiously in the following cases: In patients with hepatic or renal failure, in patients taking other hepatotoxic medication. Prolonged

use of the drug without consulting a physician should be avoided.

Preparation:

Paracetamol 500 mg & Caffeine 65 mg.