Thursday, August 7, 2014

Aminosol IV

Aminosol IV


Each 100ml solution contains i) Active Ingredients: L-Isoleucine USP 352 mg, L-Leucine USP 490 mg, L-Lysine Hydrochloride USP 430 mg, L-Methionine USP 225 mg, L-Phenylalanine USP 533 mg, L-Threonine USP 250 mg, L-Tryptophan USP 90 mg, L-Valine USP 360 mg, L-Arginine Hydrochloride USP 500mg, L-Histidine Hydrochloride Monohydrate USP 250 mg, L-Aspartic Acid USP 250 mg, L-Glutamic Acid USP 75mg, L-Alanine USP 200 mg, L-Cystine USP 10mg, Glycine USP 760mg,L- Proline USP 100 mg, L-Serine USP 100 mg, L-Tyrosine USP 25 mg ii) Excipients: D-Sorbitol BP 5.0 g, Sodium Chloride BP 234mg, Potassium Acetate BP 245mg, Magnesium Chloride Hexahydrate 51mg.


Aminosol IV is a sterile, nonpyrogenic amino acid solution. It is consisting of 18 essential & non-essential amino acids with D-Sorbitol & major electrolytes needed for human body. Aminosol IV helps to preserve protein and reduce catabolism in stress conditions where oral intake is inadequate. Each Litre of solution provides 371.14 Kcal of energy & 7.2g of nitrogen.


Aminosol IV Infusion is indicated in the compensation of nitrogen loss in the following conditions, such as • Prophylaxis and therapy for protein deficiency • Burns •Trauma • Parenteral nutrition for pre & post operative support • Cancer • HIV infection • Sepsis • Impossible oral feeding and • G.I. Tract disorders: short gut syndrome, inflammatory bowel disease, tumors, pancreatitis, fistula, ulcerative colitis etc.

Dosage And Administration:

Aminosol IV should be given at the rate of 30 to 60 drops /minutes
intravenously once or several times daily depending on age, body weight & condition of the patient. The recommended intravenous dose for adults is 20ml to 34ml/kg body weight & children is 28ml to 35ml/kg body weight is generally sufficient to satisfy protein needs and promote positive nitrogen balance.

Use in Pregnancy & Lactation :

It is not known whether amino acid solution can cause fetal harm when
administered to a pregnant woman. Amino Acid solution should be given to a pregnant woman only if clearly needed. Caution should be exercised when Amino Acid Solution is administered to a nursing woman.

Side-effects :

Amino acid solution is usually well tolerated. Local hypersensitive reactions like- erythema, phlebitis and thrombosis of the chosen vein is always a possibility with intravenous infusion. If infusion is protracted, then another vein should be selected after 12-24 hours. Fever and nausea also have been reported during peripheral infusions of amino acid solutions.


This preparation should not be used in patients with hepatic coma or metabolic
disorders involving impaired nitrogen utilization.


Intravenous infusion of amino acid solution may induce a rise in blood urea nitrogen (BUN), especially in patients with impaired hepatic or renal function. Appropriate laboratory tests should be performed periodically and infusion discontinued if BUN levels exceed normal prandial limits and continue to rise. Care should be taken to avoid excess fluid accumulation, particularly in patients with renal disease, pulmonary insufficiency and heart disease.


To avoid unwanted health hazard, check the bottle against light before administration. Use sterile, non-pyrogenic Infusion Set. Not to be used if any turbidity observed in the solution or any particle(s)found in the bottle. Discard any unused portion.


Aminosol IV is supplied in 500 ml glass bottle


Store between 15oC to 25oC temperature in a dry place, protect from light. Keep out of the reach of Children.


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