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Thursday, August 7, 2014

Dextrose Anhydrous




Dextrose Anhydrous 10g

Composition:

Each 100ml solution contains Dextrose Anhydrous 10g as Dextrose Monohydrate USP and Sodium Chloride BP 0.225g

Description:

Dextrose Anhydrous 10g Injection is a sterile and non-pyrogenic solution, which restores blood glucose levels and provides calories. It may aid in minimizing liver glycogen depletion and exerts a protein sparing action.

Sodium chloride in water dissociates into sodium and chloride ions. Sodium is the principal caption of the extracellular fluid and plays important role in fluid therapy and electrolyte disturbances. Chloride has an integral role in buffering action when oxygen and carbon dioxide exchange occurs in the red blood cells.

Indications:

Dextrose Anhydrous 10g Injection is indicated for parenteral replenishment of
Fluid, Carbohydrate Calories and Sodium Chloride of the patient.


Dosage and Administration :

Dextrose Anhydrous 10g Injection should be given at the rate of 30 to 60 drops/minute intravenously depending on age, body weight and condition of the patients or as directed by the physician


Side-effect :

Thrombosis of the chosen vein is always a possibility with intravenous infusion, if infusion is protracted, then another vein should be selected after 12-24 hours.


Precaution :

To avoid unwanted health hazard, check the bottle against light before administration. Use sterile and non-pyrogenic Infusion Set. Not be used if any turbidity observed in the solution or found any particle (s) in the bottle. Discard any unused portion.


Presentation:

Dextrose Anhydrous 10g Injection is available in 500 ml & 1000ml polyethylene bottle

Storage :

Store in a cool & dry place, protect from light. Keep out of the reach of children



Composition: Each ml of Solution contains Tropicamide BP 8mg &
Phenylephrine Hydrochloride BP 50 mg.
Description: Tropicamide Plus are the combination of Tropicamide &
Phenylephrine. Tropicamide is an anti-cholinergic drug having mydriatic
and some cycloplegic action and Phenylephrine is a α1 adrenergic
receptor agonist used primarily as an agent to dilate the pupil.
Tropicamide Plus has a rapid onset of action and a short duration of
effect. Tropicamide plus eye drops are excellent to dilate the pupil for
examination of the fundus of the eye. It is also used before and after
surgical procedure of the eye.
Indications: Tropicamide Plus eye drops are indicated for –•
Examination of fundus • Retinal Photography • Cycloplegic Refraction.
• Prior to Ocular Surgery. • As an adjunct in the treatment of anterior
uveitis
Dosage and Administration: Instill 1-2 drops into the eye 15-30
minutes prior to procedure or as directed by the physician.
Side effects: On topical application there may be transient burning or
stinging sensation and lacrimation. Blurred Vision, photophobia and
allergic reactions may occur.
Precaution: After applying this medicine to the eyes, pupils will become
unusually large. It causes eyes to become more sensitive to light. So,
wear sunglasses to go out during the day time, even on cloudy days.
Contra-indications: Tropicamide Plus Eye Drops are contra-indicated
in patients with known hypersensitivity to any of its component
Presentation: Tropicamide Plus Eye Drops are supplied in 5 ml
Polyethylene bottle.
Storage: Keep in a dry & cool place, protect from light. Keep out of
the reach of the children

Aminosol IV



Aminosol IV


Composition:

Each 100ml solution contains i) Active Ingredients: L-Isoleucine USP 352 mg, L-Leucine USP 490 mg, L-Lysine Hydrochloride USP 430 mg, L-Methionine USP 225 mg, L-Phenylalanine USP 533 mg, L-Threonine USP 250 mg, L-Tryptophan USP 90 mg, L-Valine USP 360 mg, L-Arginine Hydrochloride USP 500mg, L-Histidine Hydrochloride Monohydrate USP 250 mg, L-Aspartic Acid USP 250 mg, L-Glutamic Acid USP 75mg, L-Alanine USP 200 mg, L-Cystine USP 10mg, Glycine USP 760mg,L- Proline USP 100 mg, L-Serine USP 100 mg, L-Tyrosine USP 25 mg ii) Excipients: D-Sorbitol BP 5.0 g, Sodium Chloride BP 234mg, Potassium Acetate BP 245mg, Magnesium Chloride Hexahydrate 51mg.


Description:

Aminosol IV is a sterile, nonpyrogenic amino acid solution. It is consisting of 18 essential & non-essential amino acids with D-Sorbitol & major electrolytes needed for human body. Aminosol IV helps to preserve protein and reduce catabolism in stress conditions where oral intake is inadequate. Each Litre of solution provides 371.14 Kcal of energy & 7.2g of nitrogen.


Indications:

Aminosol IV Infusion is indicated in the compensation of nitrogen loss in the following conditions, such as • Prophylaxis and therapy for protein deficiency • Burns •Trauma • Parenteral nutrition for pre & post operative support • Cancer • HIV infection • Sepsis • Impossible oral feeding and • G.I. Tract disorders: short gut syndrome, inflammatory bowel disease, tumors, pancreatitis, fistula, ulcerative colitis etc.


Dosage And Administration:

Aminosol IV should be given at the rate of 30 to 60 drops /minutes
intravenously once or several times daily depending on age, body weight & condition of the patient. The recommended intravenous dose for adults is 20ml to 34ml/kg body weight & children is 28ml to 35ml/kg body weight is generally sufficient to satisfy protein needs and promote positive nitrogen balance.


Use in Pregnancy & Lactation :

It is not known whether amino acid solution can cause fetal harm when
administered to a pregnant woman. Amino Acid solution should be given to a pregnant woman only if clearly needed. Caution should be exercised when Amino Acid Solution is administered to a nursing woman.

Side-effects :

Amino acid solution is usually well tolerated. Local hypersensitive reactions like- erythema, phlebitis and thrombosis of the chosen vein is always a possibility with intravenous infusion. If infusion is protracted, then another vein should be selected after 12-24 hours. Fever and nausea also have been reported during peripheral infusions of amino acid solutions.


Contra-indications:

This preparation should not be used in patients with hepatic coma or metabolic
disorders involving impaired nitrogen utilization.


Precaution:

Intravenous infusion of amino acid solution may induce a rise in blood urea nitrogen (BUN), especially in patients with impaired hepatic or renal function. Appropriate laboratory tests should be performed periodically and infusion discontinued if BUN levels exceed normal prandial limits and continue to rise. Care should be taken to avoid excess fluid accumulation, particularly in patients with renal disease, pulmonary insufficiency and heart disease.


Warnings:


To avoid unwanted health hazard, check the bottle against light before administration. Use sterile, non-pyrogenic Infusion Set. Not to be used if any turbidity observed in the solution or any particle(s)found in the bottle. Discard any unused portion.

Presentation:

Aminosol IV is supplied in 500 ml glass bottle

Storage:

Store between 15oC to 25oC temperature in a dry place, protect from light. Keep out of the reach of Children.

Friday, August 1, 2014

Sodium Hypochlorite


Sodium Hypochlorite

Composition :

Each ml of solution contains Sodium Hypochlorite 5mg.

Description :

Sodium Hypochlorite Solution is a disinfectant with arapid potent anti-microbial action. It is used to eliminate microorganisms from drinking water. Chlorine is one of the most effective chemicals for the control of water–borne disease.

Mode of Action :

Sodium Hypochlorite forms Sodium Hydroxide and Hypochlorous acid in Solution, where HOCl acts as the active biocidal agent. HOCl easily diffuse through the cell walls of microorganisms due to their neutral charge and small size. HOCl then react with the enzyme Glyceraldehyde- 3- phosphate dehydrogenase. This effectively
destroys the microorganism’s ability to function.


Indications :

Clotech-D is used to make drinking water safe. Dosage and Administration : In case of tap water- add 8 drops in one
liter of water and in case of river/ pond water- add 16 drops in one liter of water, wait 30 minutes and then drink.
Side effects : Sodium Hypochlorite may causes irritation and corrosion of mucous membranes with pain and vomiting, oedema of the pharynx and larynx and rarely perforation of the oesophagus and stomach.


Contra-indications :

Sodium Hypochlorite is contra-indicated in eye, ear or nose.

Presentation :

Clotech-D drops are supplied in 10 ml polyethylene bottle.

Storage :
Store at controlled room temperature in dry place. Keep out of the reach of children

Tropicamide BP


Tropicamide BP


Composition:

Each ml of Solution contains Tropicamide BP 8mg & Phenylephrine Hydrochloride BP 50 mg.

Description:

Tropicamide Plus are the combination of Tropicamide & Phenylephrine. Tropicamide is an anti-cholinergic drug having mydriatic and some cycloplegic action and Phenylephrine is a α1 adrenergic receptor agonist used primarily as an agent to dilate the pupil. Tropicamide Plus has a rapid onset of action and a short duration of effect. Tropicamide plus eye drops are excellent to dilate the pupil for examination of the fundus of the eye. It is also used before and after surgical procedure of the eye.


Indications:

Tropicamide Plus eye drops are indicated for –• Examination of fundus • Retinal Photography • Cycloplegic Refraction. • Prior to Ocular Surgery. • As an adjunct in the treatment of anterior uveitis


Dosage and Administration:

Instill 1-2 drops into the eye 15-30 minutes prior to procedure or as directed by the physician.

Side effects:

On topical application there may be transient burning or stinging sensation and lacrimation. Blurred Vision, photophobia and allergic reactions may occur.


Precaution:

After applying this medicine to the eyes, pupils will become unusually large. It causes eyes to become more sensitive to light. So, wear sunglasses to go out during the day time, even on cloudy days.


Contra-indications:

Tropicamide Plus Eye Drops are contra-indicated in patients with known hypersensitivity to any of its component

Presentation:

Tropicamide Plus Eye Drops are supplied in 5 ml Polyethylene bottle.

Storage:

Keep in a dry & cool place, protect from light. Keep out of the reach of the children

Thursday, July 31, 2014

Xylometazoline



Xylometazoline

Composition :

Each ml of solution contains Xylometazoline Hydrochloride BP 1 mg or 0.5 mg.

Description :

Xylometazoline is a nasal decongestant that is directly dosed into the nose as drops. The drug works by constricting the blood vessel in the nose. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out. So, less discharge is made.

Indications :

It is indicated for the temporary relief of nasal congestion or stuffiness in the nose due to • cold • hay fever • sinusitis • other upper respiratory allergies.


Dosage and Administration :

Adults and Children (12 years of age and older) –Use 2 to 3 drops of 0.1% solution in each nostril every 8 to 10 hours as needed. Children (2 to 12 years of age)- use 2 to 3 drops of 0.05% solution in each nostril every 8 to 10 hours as needed.


Side effects :

Side effect may occur that usually do not need medical attention. These side effects may go away during treatment as the body adjusts to the medicine. However, consult with the physician if any of the following side effects continue i.e. burning, dryness or stinging inside the nose & sneezing.


Contra-indications :

Hypersensitivity to any component of the formulation. It should not be used for people with high blood pressure or other heart problems.


Precaution :

Do not use it more often. To do so may make stuffy nose worse (rebound congestion) and the vessels become resistant or the number of receptors decrease or degenerative changes in nasal mucous membranes may occur.

Presentation :

Xylometazoline 0.05% & 0.1% nasal drops are supplied in 10 ml polyethylene bottle.

Storage :

Store at controlled room temperature in dry place. Keep out of the reach of children.

Monday, July 7, 2014

Nitroglycerin




Indication:

Indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease.

Dosage and Administration:

One tablet should be dissolved under the tongue at the first sign of an acute anginal attack. The dose may be repeated approximately every five minutes, until relief is obtained. If the pain persists after a total of 3 tablets in a 15-minute period, prompt medical attention is recommended. Injection: The usual dose range is 10 -200 mcg/min. Dose up to 400 mcg/min may be required during some surgical procedures.


Contraindication & Precaution:

Contraindicated in patients with early myocardial infarction, severe anemia, increased intracranial pressure and those with a known hypersensitivity to Nitroglycerin. Also contraindicated in patients who are using sildenafil citrate since sildenafil citrate has been shown to potentiate the hypotensive Effects of organic nitrates. Only the smallest dose required for Effective control of the acute angina attack should be used. Excessive use may lead to the development of tolerance. This drug should be used with caution in patients who may be volume-depleted or are already hypotensive.


Drug Interaction:


Antihypertensive drugs, beta-adrenergic blockers, phenothiazines, calcium channel blockers, alcohol, aspirin, ergotamine and related drugs.


Side Effect:

Headache which may be severe and persistent may occur immediately after use. Vertigo, dizziness, weakness, palpitation and other manifestations of postural hypotension may developoccasionally.


Use in Pregnancy & Lactation:

Should be given to a pregnant woman only if clearly needed. It is not known whethernitroglycerin is excreted in human milk.

Preparation:

0.5 mg Sublingual Tablet, 5 mg/ ml IV Injection, 2.6 mg SR (Sustained Release) Tablet.