Azithromycin

Indication

Bronchitis and pneumonia, sinusitis and pharyngitis/ tonsillitis, otitis media, skin and soft tissue infections, sexually transmitted diseases.


Dosage & Administration

Adults: 500 mg once daily for 3 days. Children: 10 mg/ kg body weight once daily for 3 days.


Contraindication & Precaution


Known hypersensitivity, should not be used in patients with hepatic disease Avoid concomitant administration with terfenadine or astemizole. Precaution should be taken in patients with more severe renal impairment.


Side Effect

Nausea, vomiting, abdominal discomfort (pain/cramps), flatulence, diarrhea, headache, dizziness and skin rashes, reversible elevations in liver transaminases.


Drug Interaction


Antacids, Ergot Derivatives, Digoxin & Cyclosporin, Antihistamines.


Use in Pregnancy and Lactation

The initial treatment of chlamydial cervicitis in pregnancy. In other infections, azithromycin should be used only when clearly needed. Exercise caution when administering to a nursing woman.


Preparation

500 mg Tablet, 250 mg Capsule, 200 mg/5 ml Suspension. patients. Other adverse reactions were reported burning, stinging and irritation upon instillation, contact dermatitis, corneal erosion, dry eye, dysgeusia, nasal congestion, ocular discharge, punctuate keratitis, and sinusitis in less than 1% of patients.