What Is Cancer?
Cancer
is the general name for a group of more than 100 diseases. Although there are
many kinds of cancer, all cancers start because abnormal cells grow out of
control. Untreated cancers can cause serious illness and death.
Normal cells in the body
The
body is made up of trillions of living cells. Normal body cells grow, divide to
make new cells, and die in an orderly way. During the early years of a person’s
life, normal cells divide faster to allow the person to grow. After the person
becomes an adult, most cells divide only to replace worn-out or dying cells or
to repair injuries.
How cancer starts
Cancer
starts when cells in a part of the body start to grow out of control. Cancer
cell growth is different from normal cell growth. Instead of dying, cancer
cells continue to grow and form new, abnormal cells. Cancer cells can also
invade (grow into) other tissues, something that normal cells can’t do. Growing
out of control and invading other tissues are what makes a cell a cancer cell.
Cells
become cancer cells because of DNA (deoxyribonucleic acid) damage. DNA is in
every cell and it directs all its actions. In a normal cell, when DNA is
damaged the cell either repairs the damage or dies. In cancer cells, the
damaged DNA is not repaired, but the cell doesn’t die like it should. Instead,
the cell goes on making new cells that the body doesn’t need. These new cells
all have the same damaged DNA as the first abnormal cell does.
People
can inherit abnormal DNA (it’s passed on from their parents), but most often
DNA damage is caused by mistakes that happen while the normal cell is
reproducing or by something in the environment. Sometimes the cause of the DNA
damage may be something obvious like cigarette smoking or sun exposure. But it’s rare to know exactly what
caused any one person’s cancer.
In
most cases, the cancer cells form a tumor. Over time, the tumors can replace
normal tissue, crowd it, or push it aside. Some cancers, like leukemia, rarely form tumors. Instead, these
cancer cells involve the blood and blood-forming organs and circulate through
other tissues where they grow.
Origins of Cancer
All cancers begin in cells, the body's basic unit of life.
To understand cancer, it's helpful to know what happens when normal cells
become cancer cells.The body is made up of many types of cells. These cells grow and divide in a controlled way to produce more cells as they are needed to keep the body healthy. When cells become old or damaged, they die and are replaced with new cells.
However, sometimes this orderly process goes wrong. The genetic material (DNA) of a cell can become damaged or changed, producing mutations that affect normal cell growth and division. When this happens, cells do not die when they should and new cells form when the body does not need them. The extra cells may form a mass of tissue called a tumor.
Not
all tumors are cancerous; tumors can be benign or malignant.
- Benign tumors aren't
cancerous. They can often be removed, and, in most cases, they do not come
back. Cells in benign tumors do not spread to other parts of the body.
- Malignant tumors are cancerous.
Cells in these tumors can invade nearby tissues and spread to other parts
of the body. The spread of cancer from one part of the body to another is
called metastasis.
Some
cancers do not form tumors. For example, leukemia is a cancer of the bone
marrow and blood.
How cancer spreads
Cancer
cells often travel to other parts of the body where they can grow and form new
tumors. This happens when the cancer cells get into the body’s bloodstream or
lymph vessels. The process of cancer spreading is called metastasis.
No
matter where a cancer may spread, it’s always named based on the place where it
started. For example, colon cancer that has spread to the liver is called
metastatic colon cancer, not liver cancer. In this case, cancer cells taken
from the liver would be the same as those in the colon. They would be treated
in the same ways too.
How cancers differ
Different
types of cancer can behave very differently. For instance, lung
cancer and
skin cancer are very different diseases. They grow
at different rates and respond to different treatments. This is why people with
cancer need treatment that’s aimed at their kind of cancer.
Tumors that are not cancer
A
tumor is an abnormal lump or collection of cells, but not all tumors are
cancer. Tumors that are n’t cancer are called benign. Benign tumors can
cause problems – they can grow very large and press on healthy organs and
tissues. But they can’t grow into (invade) other tissues. Because they can’t
invade, they also can’t spread to other parts of the body (metastasize). These
tumors are seldom life threatening.
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