Sunday, October 19, 2014
LISINOPRIL
GENERIC NAME(S): LISINOPRIL
Uses
Lisinopril is used to treat high blood
pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart
attacks, and kidney problems. It is also used to treat heart failure and to
improve survival after a heart attack.
Lisinopril is an ACE inhibitor and works by
relaxing blood vessels so that blood can flow more easily.
OTHER USES: This section contains uses of
this drug that are not listed in the approved professional labeling for the
drug but that may be prescribed by your health care professional. Use this drug
for a condition that is listed in this section only if it has been so
prescribed by your health care professional.
This medication may also be used to help
protect the kidneys from harm due to diabetes.
How to use lisinopril
Take
this medication by mouth with or without food as directed by your doctor,
usually once daily.
If
you are using the suspension form of this medication, shake the bottle well
before each dose. Carefully measure the dose using a special measuring
device/spoon. Do not use a household spoon because you may not get the correct
dose.
The
dosage is based on your medical condition and response to treatment. For
children, the dosage is also based on weight.
Use
this medication regularly in order to get the most benefit from it. To help you
remember, take it at the same time each day. It is important to continue taking
this medication even if you feel well. Most people with high blood pressure do
not feel sick.
For
the treatment of high blood pressure, it may take 2 to 4 weeks before you get
the full benefit of this medication. For the treatment of heart failure, it may
take weeks to months before you get the full benefit of this medication. Tell
your doctor if your condition does not improve or if it worsens (such as your
blood pressure readings remain high or increase).
What conditions does lisinopril treat?
Side Effects
Dizziness, lightheadedness, tiredness, or headache
may occur as your body adjusts to the medication. Dry cough may also occur. If
any of these effects persist or worsen, tell your doctor or pharmacist
promptly.
Remember that your doctor has prescribed this
medication because he or she has judged that the benefit to you is greater than
the risk of side effects. Many people using this medication do not have serious
side effects.
Tell your doctor right away if any of these
unlikely but serious side effects occur: fainting, symptoms of a high potassium
blood level (such as muscle weakness, slow/irregular heartbeat), signs of
infection (such as fever, chills, persistent sore throat), change in the amount
of urine.
This drug may rarely cause serious (possibly
fatal) liver problems. Tell your doctor right away if you notice any of the
following rare but serious side effects: yellowing eyes/skin, dark
urine, severe stomach/abdominal pain, persistent nausea/vomiting.
A
very serious allergic reaction
to this drug is rare. However, get medical help right away if you notice any
symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This
is not a complete list of possible side effects. If you notice other effects
not listed above, contact your doctor or pharmacist.
In
the US -
Call
your doctor for medical advice about side effects. You may report side effects
to FDA at 1-800-FDA-1088.
In
Canada - Call your doctor for medical advice about side effects. You may report
side effects to Health Canada at 1-866-234-2345.
List lisinopril side effects by likelihood and severity.
Precautions
Before
taking lisinopril, tell your doctor or pharmacist if you are allergic to it; or
to other ACE inhibitors (such as benazepril);
or if you have any other allergies. This product may contain inactive
ingredients, which can cause allergic reactions or other problems. Talk to your
pharmacist for more details.
Before
using this medication, tell your doctor or pharmacist your medical history,
especially of: history of an allergic reaction which included swelling of the
face/lips/tongue/throat (angioedema), blood filtering procedures (such as LDL
apheresis, dialysis), high level of potassium in the blood, collagen vascular
disease (such as lupus, scleroderma).
This
drug may make you dizzy. Do not drive, use machinery, or do any activity that
requires alertness until you are sure you can perform such activities safely.
Limit alcoholic beverages.
To
reduce the risk of dizziness and lightheadedness, get up slowly when rising
from a sitting or lying position.
Too
much sweating, diarrhea, or vomiting may cause loss of too much body water (dehydration)
and increase your risk of lightheadedness. Report prolonged diarrhea or
vomiting to your doctor. Be sure to drink enough fluids to prevent dehydration
unless your doctor directs you otherwise.
Before
having surgery, tell your doctor or dentist about all the products you use
(including prescription drugs, nonprescription drugs, and herbal products).
This
product may increase your potassium levels. Before using potassium supplements
or salt substitutes that contain potassium, consult your doctor or pharmacist.
Older
adults may be more sensitive to the side effects of this drug, including
dizziness and increases in potassium level.
This
medication is not recommended for use during pregnancy. It may harm an unborn
baby. Consult your doctor for more details. (See also Warning section.)
It
is unknown if this medication passes into breast milk. Consult your doctor
before breast-feeding.
What should I know
regarding pregnancy, nursing and administering lisinopril to children or the
elderly?
Interactions
See
also Precautions section.
Drug
interactions may change how your medications work or increase your risk for
serious side effects. This document does not contain all possible drug
interactions. Keep a list of all the products you use (including
prescription/nonprescription drugs and herbal products) and share it with your
doctor and pharmacist. Do not start, stop, or change the dosage of any
medicines without your doctor's approval.
Some
products that may interact with this drug include: aliskiren, lithium, drugs
that may increase the level of potassium in the blood (such as ARBs including
losartan/valsartan, birth control pills containing drospirenone).
Check
the labels on all your medicines (such as cough-and-cold products, diet aids,
or NSAIDs such as ibuprofen, naproxen) because they may contain ingredients
that could increase your blood pressure or worsen your heart failure. Ask your
pharmacist for more details.
A
very serious reaction may occur if you are getting injections for bee/wasp
sting allergy (desensitization) and are also taking lisinopril. Make sure all
your doctors know which medicines you are using.
Does lisinopril
interact with other medications?
Overdose
If
overdose is suspected, contact a poison control center or emergency room
immediately. US residents can call their local poison control center at
1-800-222-1222. Canada residents can call a provincial poison control center.
Symptoms of overdose may include: severe dizziness, fainting.
Notes
Do
not share this medication with others.
Lifestyle
changes such as stress reduction programs, exercise and dietary changes may
increase the effectiveness of this medicine. Talk to your doctor or pharmacist
about lifestyle changes that might benefit you.
Laboratory
and/or medical tests (such as kidney function, potassium levels) should be
performed periodically to monitor your progress or check for side effects.
Consult your doctor for more details.
Saturday, September 27, 2014
Cancer prevention nutrition or diet tips and Cancer-Fighting Foods
Whether you have a history of cancer in your family, or are
currently battling the disease, lifestyle factors, including your diet, can
make a huge difference in helping you fight off cancer. Some foods actually
increase your risk of cancer, while others support your body and strengthen
your immune system. By making smart food choices, you can protect your health,
feel better, and boost your ability fight off cancer and other disease
What you need to know about cancer and diet
Not all health problems are avoidable, but you have more
control over your health than you may think. Research shows that a large
percentage of cancer-related deaths—maybe even the majority—are directly linked
to lifestyle choices such as smoking, drinking, a lack of exercise, and an
unhealthy diet. Avoiding cigarettes, limiting alcohol, and getting regular
exercise are a great start to an anti-cancer lifestyle. But to best support
your health, you also need to look at your eating habits.What you eat—and don’t eat—has a powerful effect on your health, including your risk of cancer. Without knowing it, you may be eating many foods that fuel cancer, while neglecting the powerful foods and nutrients that can protect you. If you change your diet and behaviors, you can minimize your risk of disease and possibly even stop cancer in its tracks.
Cancer prevention diet tip # 1: Focus on plant-based foods
The less processed these foods are—the less they’ve been cooked, peeled, mixed with other ingredients, stripped of their nutrients, or otherwise altered from the way they came out of the ground—the better.
There are many ways to add plant-based foods to your diet. A nice visual reminder is to aim for a plate of food that is filled at least two-thirds with whole grains, vegetables, beans, or fruit. Dairy products, fish, and meat should take up no more than a third of the plate. Keep in mind that you don’t need to go completely vegetarian. Instead, focus on adding “whole” foods, which are foods close to their original form. Just as important, try to minimize or reduce the amount of processed foods you eat. Eat an apple instead of drinking a glass of apple juice, for example. Or enjoy a bowl of oatmeal with raisins instead of an oatmeal raisin cookie.
Simple tips for getting more plant-based foods in your diet
- Breakfast:
Add
fruit and a few seeds or nuts to your whole grain breakfast cereal (such
as oatmeal).
- Lunch: Eat a big salad filled
with your favorite beans and peas or other combo of veggies. Always order
lettuce and tomato (plus any other veggies you can) on your sandwiches.
Order whole grain bread for your sandwiches. Have a side of veggies like
cut up carrots, sauerkraut, or a piece of fruit.
- Snacks: Fresh fruit and
vegetables. Grab an apple or banana on your way out the door. Raw veggies
such as carrots, celery, cucumbers, jicama, peppers, etc. are great with a
low-fat dip such as hummus. Keep trail mix made with nuts, seeds, and a
little dried fruit on hand.
- Dinner: Add fresh or frozen
veggies to your favorite pasta sauce or rice dish. Top a baked potato with
broccoli and yogurt, sauteed veggies, or with salsa. Replace creamy pasta
sauces, with sauteed vegetables or tomato sauce made with healthy olive
oil.
- Dessert: Choose fruit instead
of a richer dessert. Or a single square of dark chocolate.
Cancer prevention diet tip # 2: Bulk up on fiber
Fiber is found in fruits, vegetables, and whole grains. In general, the more natural and unprocessed the food, the higher it is in fiber. There is no fiber in meat, dairy, sugar, or “white” foods like white bread, white rice, and pastries.
Simple ways to add more fiber to your diet:
- Use brown rice instead
of white rice
- Substitute whole-grain
bread for white bread
- Choose a bran muffin
over a croissant or pastry
- Snack on popcorn
instead of potato chips
- Eat fresh fruit such as
a pear, a banana, or an apple (with the skin)
- Have a baked potato, including
the skin, instead of mashed potatoes
- Enjoy fresh carrots,
celery, or bell peppers with a hummus or salsa, instead of chips and a
sour cream dip
- Use beans instead of
ground meat in chili, casseroles, tacos, and even burgers (bean burgers
can taste great)
High-fiber,
cancer-fighting foods |
|
Whole
grains-- |
whole-wheat pasta, raisin bran, barley, oatmeal, oat bran
muffins, popcorn, brown rice, whole-grain or whole-wheat bread |
Fruit------------- |
raspberries, apples, pears, strawberries, bananas,
blackberries, blueberries, mango, apricots, citrus fruits, dried fruit,
prunes, raisins |
Legumes--------
|
lentils, black beans, split peas, lima beans, baked beans,
kidney beans, pinto, chick peas, navy beans, black-eyed peas |
Vegetables----- |
broccoli, spinach, dark green leafy vegetables, peas,
artichokes, corn, carrots, tomatoes, Brussels sprouts, potatoes |
Cancer prevention diet tip # 3: Cut down on meat
Research shows that vegetarians are about fifty percent less
likely to develop cancer than those who eat meat. So what’s the link between
meat and cancer risk? First, meat lacks fiber and other nutrients that have
been shown to have cancer-protective properties. What it does have in
abundance, however, is fat—often very high levels of saturated fat. High-fat
diets have been linked to higher rates of cancer. And saturated fat is
particularly dangerous. Finally, depending on how it is prepared, meat can
develop carcinogenic compounds.
Making better meat and protein choices
You don’t need to cut out meat completely and become a
vegetarian. But most people consume far more meat than is healthy. You can cut
down your cancer risk substantially by reducing the amount of animal-based
products you eat and by choosing healthier meats.- Keep
meat to a minimum. Try to keep the total amount of meat in your
diet to no more than fifteen percent of your total calories. Ten percent
is even better.
- Eat
red meat only occasionally. Red meat is high in saturated fat, so eat it
sparingly.
- Reduce
the portion size of meat in each meal. The portion should be
able to fit in the palm of your hand.
- Use
meat as a flavoring or a side, not the entree. You can use a little
bit of meat to add flavor or texture to your food, rather than using it as
the main element.
- Add
beans and other plant-based protein sources to your meals.
- Choose
leaner meats, such as fish, chicken, or turkey. If possible, buy organic.
- Avoid
processed meats such as hot dogs, sausage, deli meats, and salami.
Cancer prevention diet tip #4:
Choose your fats wisely
A major benefit of cutting down on the amount of meat you
eat is that you will automatically cut out a lot of unhealthy fat. Eating a
diet high in fat increases your risk for many types of cancer. But cutting out
fat entirely isn’t the answer, either. In fact, some types of fat may actually
protect against cancer. The trick is to choose your fats wisely and eat them in
moderation.- Fats
that increase cancer risk – The two most damaging fats are saturated
fats and Trans fats. Saturated fats are found mainly in animal products
such as red meat, whole milk dairy products, and eggs. Trans fats, also
called partially hydrogenated oils, are created by adding hydrogen to
liquid vegetable oils to make them more solid and less likely to
spoil—which is very good for food manufacturers, and very bad for you.
- Fats
that decrease cancer risk – The best fats are unsaturated fats, which
come from plant sources and are liquid at room temperature. Primary
sources include olive oil, canola oil, nuts, and avocados. Also focus on
omega-3 fatty acids, which fight inflammation and support brain and heart
health. Good sources include salmon, tuna, and flax seeds.
Tips for choosing cancer-fighting fats and avoiding the bad
- Reduce
your consumption of red meat, whole milk, butter, and eggs, as these are the
primary source of saturated fats.
- Cook
with olive oil instead of regular vegetable oil. Canola oil is another
good choice, especially for baking.
- Check
the ingredient list on food labels and avoid anything with hydrogenated or
partially hydrogenated oils, which are usually found in stick margarines,
shortenings, salad dressings, and other packaged foods.
- Trim
the fat off
of meat when you do eat
it, and avoid eating the skin of the chicken.
- Choose
nonfat dairy products and eggs that have been fortified with omega-3
fatty acids.
- Add
nuts and seeds to cereal, salads, soups, or other dishes. Good choices include
walnuts, almonds, pumpkin seeds, hazelnuts, pecans, and sesame seeds.
- Use flax seed oil in smoothies, salad dressings, or mixed in snacks such as
applesauce. But do not cook with flax seed oil, as it loses its protective
properties when heated.
- Limit
fast food, fried foods, and packaged foods, which tend to be high
in trans fats. This includes foods like potato chips, cookies, crackers,
French fries, and doughnuts.
- Eat
fish once or twice a week. Good choices include wild salmon, sardines,
herring, and black cod. But be conscious of mercury, a contaminant found
in many types of fish.
Cancer prevention diet tip #5:
Choose cancer-fighting foods
Your immune system keeps you healthy by fighting off
unwanted invaders in your system, including cancer cells. There are many things
you can eat to maximize the strength of your immune system, as well as many
cancer-fighting foods. But keep in mind that there is no single miracle food or
ingredient that will protect you against cancer. Eating a colorful variety
gives you the best protection. - Boost
your antioxidants. Antioxidants are powerful vitamins that protect
against cancer and help the cells in your body function optimally. Fruits
and vegetables are the best sources of antioxidants such as beta-carotene,
vitamin C, vitamin E, and selenium.
- Eat
a wide range of brightly colored fruits and vegetables. Colorful fruits and
vegetables are rich in phytochemicals, a potent disease–fighting and
immune–boosting nutrient. The greater the variety of colors that you
include, the more you will benefit, since different colors are rich in
different phytochemicals.
- Flavor
with immune-boosting spices and foods. Garlic, ginger, and
curry powder not only add flavor, but they add a cancer-fighting punch of
valuable nutrients. Other good choices include turmeric, basil, rosemary,
and coriander. Use them in soups, salads, casseroles, or any other dish.
- Drink
plenty of water. Water is essentially to all bodily processes. It stimulates the
immune system, removes waste and toxins, and transports nutrients to all
of your organs.
Cancer prevention diet tip #6: Prepare your food in healthy
ways
Choosing healthy food is not the only important factor. It
also matters how you prepare and store your food. The way you cook your food
can either help or hurt your anti-cancer efforts.
Preserving the cancer-fighting benefits of vegetables
Here are a few tips that will help you get the most benefits
from eating all those great cancer-fighting vegetables: - Eat
at least some raw fruits and vegetables. These have the highest
amounts of vitamins and minerals, although cooking some vegetables can
make the vitamins more available for our body to use.
- When
cooking vegetables, steam
until just tender using a small amount of water. This
preserves more of the vitamins. Overcooking vegetables removes many of the
vitamins and minerals. If you do boil vegetables, use the cooking water in
a soup or another dish to ensure you’re getting all the vitamins.
- Wash
all fruits and vegetables. Use a vegetable brush for washing. Washing
does not eliminate all pesticide residue, but will reduce it. Choose
organic produce if possible, grown without the use of pesticides.
Cooking and carcinogens
Carcinogens are cancer-causing substances found in food.
Carcinogens can form during the cooking or preserving process—mostly in
relation to meat—and as foods start to spoil. Examples of foods that have
carcinogens are cured, dried, and preserved meats (e.g. bacon, sausage, beef
jerky); burned or charred meats; smoked foods; and foods that have become
moldy. Here are some ways reduce your exposure to carcinogens: - Do not cook oils
on high heat. Low-heat cooking or baking (less than 240 degrees)
prevents oils or fats from turning carcinogenic. Instead of deep-frying,
pan-frying, and sauteing, opt for healthier methods such as baking,
boiling, steaming, or broiling.
- Go easy on the
barbecue.
Burning or charring meats creates carcinogenic substances. If you do
choose to barbecue, don’t overcook the meat and be sure to cook at the
proper temperature (not too hot).
- Store oils in a
cool dark place in airtight containers, as they quickly become rancid
when exposed to heat, light, and air.
- Choose fresh
meats
instead of cured, dried, preserved, or smoked meats.
- Avoid foods that
look or smell moldy, as they likely contain aflatoxin, a strong carcinogen.
Aflatoxin is most commonly found on moldy peanuts. Nuts will stay fresh
longer if kept in the refrigerator or freezer.
- Be careful what
you put in the microwave. Use waxed paper rather than
plastic wrap to cover your food in the microwave. And always use
microwave-safe containers.
Take cancer prevention into your own hands
Take
cancer prevention into your own hands
You've probably heard conflicting reports about cancer prevention. Sometimes the specific cancer-prevention tip recommended in one study or news report is advised against in another.
In many cases, what is known about cancer prevention is still evolving. However, it's well accepted that your chances of developing cancer are affected by the lifestyle choices you make.
So if you're concerned about cancer prevention, take comfort in the fact that some simple lifestyle changes can make a big difference. Consider these seven cancer prevention tips.
1. Don't use tobacco
Using any type of tobacco puts you on a collision course
with cancer. Smoking has been linked to various types of cancer — including
cancer of the lung, bladder, cervix and kidney. And chewing tobacco has been
linked to cancer of the oral cavity and pancreas. Even if you don't use
tobacco, exposure to secondhand smoke might increase your risk of lung cancer.
Avoiding tobacco — or deciding to stop using it — is one of the most important health decisions you can make. It's also an important part of cancer prevention. If you need help quitting tobacco, ask your doctor about stop-smoking products and other strategies for quitting.
2. Eat a healthy diet
Although making healthy selections at the grocery store and
at mealtime can't guarantee cancer prevention, it might help reduce your risk.
Consider these guidelines:
3. Maintain a healthy weight and be physically active
Maintaining a healthy weight might lower the risk of various
types of cancer, including cancer of the breast, prostate, lung, colon and
kidney.
Physical activity counts, too. In addition to helping you control your weight, physical activity on its own might lower the risk of breast cancer and colon cancer.
Adults who participate in any amount of physical activity gain some health benefits. But for substantial health benefits, strive to get at least 150 minutes a week of moderate aerobic activity or 75 minutes a week of vigorous aerobic physical activity. You can also do a combination of moderate and vigorous activity. As a general goal, include at least 30 minutes of physical activity in your daily routine — and if you can do more, even better.
4. Protect yourself from the sun
Skin cancer is one of the most common kinds of cancer — and
one of the most preventable. Try these tips:
5. Get immunized
Cancer prevention includes protection from certain viral
infections. Talk to your doctor about immunization against:
6. Avoid risky behaviors
Another effective cancer prevention tactic is to avoid risky
behaviors that can lead to infections that, in turn, might increase the risk of
cancer. For example:
7. Get regular medical care
Regular self-exams and screenings for various types of
cancers — such as cancer of the skin, colon, prostate, cervix and breast — can
increase your chances of discovering cancer early, when treatment is most
likely to be successful. Ask your doctor about the best cancer screening
schedule for you.
Take cancer prevention into your own hands, starting today. The rewards will last a lifetime.
You've probably heard conflicting reports about cancer prevention. Sometimes the specific cancer-prevention tip recommended in one study or news report is advised against in another.
In many cases, what is known about cancer prevention is still evolving. However, it's well accepted that your chances of developing cancer are affected by the lifestyle choices you make.
So if you're concerned about cancer prevention, take comfort in the fact that some simple lifestyle changes can make a big difference. Consider these seven cancer prevention tips.
1. Don't use tobacco
Using any type of tobacco puts you on a collision course
with cancer. Smoking has been linked to various types of cancer — including
cancer of the lung, bladder, cervix and kidney. And chewing tobacco has been
linked to cancer of the oral cavity and pancreas. Even if you don't use
tobacco, exposure to secondhand smoke might increase your risk of lung cancer. Avoiding tobacco — or deciding to stop using it — is one of the most important health decisions you can make. It's also an important part of cancer prevention. If you need help quitting tobacco, ask your doctor about stop-smoking products and other strategies for quitting.
2. Eat a healthy diet
Although making healthy selections at the grocery store and
at mealtime can't guarantee cancer prevention, it might help reduce your risk.
Consider these guidelines: - Eat
plenty of fruits and vegetables. Base your diet on fruits, vegetables
and other foods from plant sources — such as whole grains and beans.
- Limit
fat.
Eat lighter and leaner by choosing fewer high-fat foods, particularly
those from animal sources. High-fat diets tend to be higher in calories
and might increase the risk of overweight or obesity — which can, in turn,
increase cancer risk.
- If
you choose to drink alcohol, do so only in moderation. The risk of various
types of cancer — including cancer of the breast, colon, lung, kidney and
liver — increases with the amount of alcohol you drink and the length of
time you've been drinking regularly.
3. Maintain a healthy weight and be physically active
Maintaining a healthy weight might lower the risk of various
types of cancer, including cancer of the breast, prostate, lung, colon and
kidney. Physical activity counts, too. In addition to helping you control your weight, physical activity on its own might lower the risk of breast cancer and colon cancer.
Adults who participate in any amount of physical activity gain some health benefits. But for substantial health benefits, strive to get at least 150 minutes a week of moderate aerobic activity or 75 minutes a week of vigorous aerobic physical activity. You can also do a combination of moderate and vigorous activity. As a general goal, include at least 30 minutes of physical activity in your daily routine — and if you can do more, even better.
4. Protect yourself from the sun
Skin cancer is one of the most common kinds of cancer — and
one of the most preventable. Try these tips: - Avoid
midday sun. Stay out of the sun between 10 a.m. and 4 p.m., when the sun's
rays are strongest.
- Stay
in the shade. When you're outdoors, stay in the shade as much as possible.
Sunglasses and a broad-brimmed hat help, too.
- Cover
exposed areas. Wear tightly woven, loose fitting clothing that covers as much of
your skin as possible. Opt for bright or dark colors, which reflect more
ultraviolet radiation than pastels or bleached cotton.
- Don't
skimp on sunscreen. Use generous amounts of sunscreen when you're
outdoors, and reapply often.
- Avoid
tanning beds and sunlamps. These are just as damaging as natural
sunlight.
5. Get immunized
Cancer prevention includes protection from certain viral
infections. Talk to your doctor about immunization against: - Hepatitis
B.
Hepatitis B can increase the risk of developing liver cancer. The
hepatitis B vaccine is recommended for certain high-risk adults — such as
adults who are sexually active but not in a mutually monogamous
relationship, people with sexually transmitted infections, intravenous
drug users, men who have sex with men, and health care or public safety
workers who might be exposed to infected blood or body fluids.
- Human
papillomavirus (HPV). HPV is a sexually transmitted virus that can
lead to cervical and other genital cancers as well as squamous cell
cancers of the head and neck. The HPV vaccine is available to both men and
women age 26 or younger who didn't have the vaccine as adolescents.
6. Avoid risky behaviors
Another effective cancer prevention tactic is to avoid risky
behaviors that can lead to infections that, in turn, might increase the risk of
cancer. For example: - Practice
safe sex. Limit your number of sexual partners, and use a condom when you
have sex. The
more sexual partners you have in your lifetime, the more likely you are to
contract a sexually transmitted infection — such as HIV or HPV. People who
have HIV or AIDS have a higher risk of cancer of the anus, liver and lung.
HPV is most often associated with cervical cancer, but it might also
increase the risk of cancer of the anus, penis, throat, vulva and vagina.
- Don't
share needles. Sharing needles with an infected drug user can lead to HIV, as
well as hepatitis B and hepatitis C — which can increase the risk of liver
cancer. If you're concerned about drug abuse or addiction, seek
professional help.
7. Get regular medical care
Regular self-exams and screenings for various types of
cancers — such as cancer of the skin, colon, prostate, cervix and breast — can
increase your chances of discovering cancer early, when treatment is most
likely to be successful. Ask your doctor about the best cancer screening
schedule for you. Take cancer prevention into your own hands, starting today. The rewards will last a lifetime.
Know about cancer diseases details
What Is Cancer?
Cancer
is the general name for a group of more than 100 diseases. Although there are
many kinds of cancer, all cancers start because abnormal cells grow out of
control. Untreated cancers can cause serious illness and death.
Normal cells in the body
The
body is made up of trillions of living cells. Normal body cells grow, divide to
make new cells, and die in an orderly way. During the early years of a person’s
life, normal cells divide faster to allow the person to grow. After the person
becomes an adult, most cells divide only to replace worn-out or dying cells or
to repair injuries.
How cancer starts
Cancer
starts when cells in a part of the body start to grow out of control. Cancer
cell growth is different from normal cell growth. Instead of dying, cancer
cells continue to grow and form new, abnormal cells. Cancer cells can also
invade (grow into) other tissues, something that normal cells can’t do. Growing
out of control and invading other tissues are what makes a cell a cancer cell.
Cells
become cancer cells because of DNA (deoxyribonucleic acid) damage. DNA is in
every cell and it directs all its actions. In a normal cell, when DNA is
damaged the cell either repairs the damage or dies. In cancer cells, the
damaged DNA is not repaired, but the cell doesn’t die like it should. Instead,
the cell goes on making new cells that the body doesn’t need. These new cells
all have the same damaged DNA as the first abnormal cell does.
People
can inherit abnormal DNA (it’s passed on from their parents), but most often
DNA damage is caused by mistakes that happen while the normal cell is
reproducing or by something in the environment. Sometimes the cause of the DNA
damage may be something obvious like cigarette smoking or sun exposure. But it’s rare to know exactly what
caused any one person’s cancer.
In
most cases, the cancer cells form a tumor. Over time, the tumors can replace
normal tissue, crowd it, or push it aside. Some cancers, like leukemia, rarely form tumors. Instead, these
cancer cells involve the blood and blood-forming organs and circulate through
other tissues where they grow.
Origins of Cancer
All cancers begin in cells, the body's basic unit of life.
To understand cancer, it's helpful to know what happens when normal cells
become cancer cells.The body is made up of many types of cells. These cells grow and divide in a controlled way to produce more cells as they are needed to keep the body healthy. When cells become old or damaged, they die and are replaced with new cells.
However, sometimes this orderly process goes wrong. The genetic material (DNA) of a cell can become damaged or changed, producing mutations that affect normal cell growth and division. When this happens, cells do not die when they should and new cells form when the body does not need them. The extra cells may form a mass of tissue called a tumor.
Not
all tumors are cancerous; tumors can be benign or malignant.
- Benign tumors aren't
cancerous. They can often be removed, and, in most cases, they do not come
back. Cells in benign tumors do not spread to other parts of the body.
- Malignant tumors are cancerous.
Cells in these tumors can invade nearby tissues and spread to other parts
of the body. The spread of cancer from one part of the body to another is
called metastasis.
Some
cancers do not form tumors. For example, leukemia is a cancer of the bone
marrow and blood.
How cancer spreads
Cancer
cells often travel to other parts of the body where they can grow and form new
tumors. This happens when the cancer cells get into the body’s bloodstream or
lymph vessels. The process of cancer spreading is called metastasis.
No
matter where a cancer may spread, it’s always named based on the place where it
started. For example, colon cancer that has spread to the liver is called
metastatic colon cancer, not liver cancer. In this case, cancer cells taken
from the liver would be the same as those in the colon. They would be treated
in the same ways too.
How cancers differ
Different
types of cancer can behave very differently. For instance, lung
cancer and
skin cancer are very different diseases. They grow
at different rates and respond to different treatments. This is why people with
cancer need treatment that’s aimed at their kind of cancer.
Tumors that are not cancer
A
tumor is an abnormal lump or collection of cells, but not all tumors are
cancer. Tumors that are n’t cancer are called benign. Benign tumors can
cause problems – they can grow very large and press on healthy organs and
tissues. But they can’t grow into (invade) other tissues. Because they can’t
invade, they also can’t spread to other parts of the body (metastasize). These
tumors are seldom life threatening.
Thursday, September 25, 2014
Side effects of asthma treatments
Side effects of relievers and presenters
Relievers are a safe and effective medicine and have few side effects, as long as they are not used too much. The main side effects include a mild shaking of the hands, headache and muscle cramps. These usually only happen with high doses of reliever inhaler and usually only last for a few minutes.
Presenters are very safe at usual doses, although they can cause a range of side effects at high doses, especially over long-term use. The main side effect of presenter inhalers is a fungal infection (oral candidacies) of the mouth or throat. You may also develop a hoarse voice. Using a spacer can help prevent these side effects. Also, rinse your mouth or clean your teeth after taking your presenter inhaler.
Your doctor or nurse will discuss with you the need to balance control of your asthma with the risk of side effects, and how to keep side effects to a minimum.
Side effects of add on therapy
Long-acting relievers may cause similar side effects to short-acting relievers, including a mild shaking of the hands, headache and muscle cramps. Your GP can discuss the risks and benefits of this drug with you. You should be monitored at the beginning of your treatment and reviewed regularly. If you find there is no benefit to using the long-acting reliever, it should be stopped.
Theophylline tablets have been known to cause side effects in some people, including headaches, nausea, insomnia, vomiting, irritability and stomach upsets. These can usually be avoided by adjusting the dose.
Leukotriene receptor agonists do not generally cause side effects, although there have been reports of stomach upsets, feeling thirsty and headache.
Side effects of steroid tablets
Oral steroids carry a risk if they are taken for more than three months or if they are taken frequently (three or four courses of steroids a year). Side effects can include:
- osteoporosis (fragile bones)
- high blood pressure (hypertension)
- diabetes
- weight gain
- cataracts and glaucoma (eye disorders)
- thinning of the skin
- easy bruising
- muscle weakness
To minimize the risk of taking oral steroids:
- Eat a healthy, balanced diet with plenty of calcium.
- Maintain a healthy body weight.
- Stop smoking (if you smoke).
- Do regular exercise.
You will also need regular appointments to check for high blood pressure, diabetes and osteoporosis.
Do you know asthma treatment? All treatment of asthma patients
Personal asthma action plan
As part of your initial assessment, you should be encouraged to draw up a personal asthma action plan with your GP or asthma nurse. If you have been admitted to hospital because of an asthma attack, you should be offered an action plan (or the opportunity to review an existing action plan) before you go home.
The action plan should include information about your asthma medicines and will help you recognize when your symptoms are getting worse and what steps to take. You should also be given information about what to do if you have an asthma attack.
Your personal asthma action plan should be reviewed with your GP or asthma nurse at least once a year, or more frequently if your symptoms are severe.
As part of your asthma plan, you may be given a peak flow meter. This will give you another way of monitoring your asthma, rather than relying only on symptoms.
Taking asthma medicines
Inhalers
Asthma medicines are usually given by inhalers, which are devices that deliver the drug directly into the airways through your mouth when you breathe in. Inhaling a drug is an effective way of taking an asthma medicine as it goes straight to the lungs, with very little ending up elsewhere in the body. However, each inhaler works in a slightly different way. You should have training from your GP or nurse in how to use your device. This should be checked at least once a year.
Spacers
Some inhalers emit an aerosol jet when pressed. These work better if given through a spacer, which can increase the amount of medication that reaches the lungs and reduces the side effects. Some people find using inhalers difficult, and spacers can help them. However, spacers are often advised even for people who use inhalers well as they improve the distribution of medication in the lungs. Spacers are plastic or metal containers with a mouthpiece at one end and a hole for the inhaler at the other. The medicine is 'puffed' into the spacer by the inhaler and then breathed in through the spacer mouthpiece. Spacers are also good for reducing the risk of thrush in the mouth or throat, which can be a side effect of inhaled asthma medicines.
Reliever inhalers
Reliever inhalers are taken to relieve asthma symptoms quickly. The inhaler usually contains a medicine called a short-acting beta2-agonist. It works by relaxing the muscles surrounding the narrowed airways. This allows the airways to open wider, making it easier to breathe again. Examples of reliever medicines include salbutamol and terbutaline. They are generally safe medicines with few side effects, unless over used. However, they should rarely be necessary if asthma is well controlled, and anyone needing to use them three or more times a week should have their treatment reviewed.
Everyone with asthma should be given a reliever inhaler, also known simply as a reliever. It is often blue.
Preventer inhalers
Preventer inhalers work over time to reduce the amount of inflammation and 'twitchiness' in the airways and prevent asthma attacks occurring. You will need to use the preventer inhaler daily for some time before you gain the full benefit. You may still occasionally need the reliever inhaler (usually blue) to relieve symptoms, but if you continue to need them often, your treatment should be reviewed.
The preventer inhaler usually contains a medicine called an inhaled corticosteroid. Examples of preventer medicines include beclometasone, budesonide, fluticasone and mometasone. Preventer inhalers are often brown, red or orange.
Preventer treatment is normally recommended if you:
- have asthma symptoms more than twice a week
- wake up once a week due to asthma symptoms
- have to use a reliever inhaler more than twice a week
Smoking can reduce the effects of preventer inhalers.
Inhaled corticosteroids can occasionally cause a mild fungal infection (oral thrush) in the mouth and throat, so rinse your mouth thoroughly after inhaling a dose. For more information on side effects, see below.
Other treatments and 'add on' therapy
Long-acting reliever inhaler
If your asthma does not respond to treatment, the dose of preventer inhaler can be increased in discussion with your healthcare team. If this does not control your asthma symptoms, you may be given an inhaler containing a medicine called a long-acting reliever (long-acting bronchodilator/long acting beta2-agonist or LABA) to take as well. Or you may be given an inhaler combining an inhaled steroid and a long-acting bronchodilator in the one device, called a 'combination' inhaler. These work in the same way as short-acting relievers, but they take longer to work and can last up to 12 hours. Examples of long-acting reliever inhalers include formoterol and salmeterol
Only use your long-acting reliever inhaler in combination with the preventer inhaler and never by itself. Studies have shown that using only a long-acting reliever can increase the chance of an asthma attack and can even increase the risk of death. Examples of combination inhalers include Seretide, Symbicort and Fostair. These are usually purple, red and white, or maroon.
Preventer medicines
If treatment of your asthma is still not successful, additional preventer medicines will be tried. Two possible alternatives include:
- leukotriene receptor antagonists (montelukast): tablets that block part of the chemical reaction involved in inflammation of the airways
- theophyllines: tablets that help widen the airways by relaxing the muscles around them
If your asthma is still not under control, you may be prescribed regular oral steroids (steroid tablets). This treatment is usually monitored by a respiratory specialist (a specialist in asthma). Long-term use of oral steroids has possible serious side effects, so they are only used once other treatment options have been tried. See below for more information on the side effects of steroid tablets.
Occasional use of oral steroids
Most people only need to take a course of oral steroids for one or two weeks. Once your asthma is under control, you can be 'stepped-down' to your previous treatment.
Omalizumab (Xolair)
Omalizumab, also known as Xolair, is the first of a new category of drugs. It binds to one of the proteins involved in the immune response and reduces its level in the blood. This reduces the chance of an immune reaction happening. The National Institute for Heath and Clinical Excellence (NICE) recommends that omalizumab can be used in people with frequent severe asthma attacks which require visits to A&E or hospital admission.
Omalizumab is given as an injection every two to four weeks. It should only be prescribed in a specialist centre. If omalizumab does not control asthma symptoms within 16 weeks, the treatment should be stopped.
Bronchial thermoplasty
Bronchial thermoplasty is a relatively new procedure not yet widely available. In some cases it may be used to treat severe asthma by reducing airway narrowing.
The procedure is carried out either with sedation or under general anesthetic. A bronchoscope (a type of hollow tube) containing a probe is inserted through the mouth or nose into the airway and expanded so it touches the airway wall and heated. Three treatment sessions are usually needed with at least three weeks between each session.
There is some evidence to show this procedure may reduce asthma attacks and improve the quality of life of someone with severe asthma. However, the long-term risks and benefits are not yet fully known.
You should discuss this procedure fully with your clinician if the treatment is offered.